Acatalasia Several rare cataphoretic variants of red cell catalase were line by Baur (1963). Nance et al. (1968) also described electrophoretic variants. information on gene frequencies of allelic variants were tabulated by Roychoudhury and Nei (1988). Wieacker et al. (1980) assigned a gene for catalase to 11p by study of man-mouse cell hybrid clones. In the hybrid cells, detection of human catalase was precluded by the complexity of the electrophoretic patterns resulting from interference by a catalase-modifying enzyme activity. Therefore, a specific antihuman antibody was expend in conjunction with electrophoresis.
In mouse, catalase is not syntenic to the beta-globin clust er or to LDH-A. Junien et al. (1980) investigated catalase gene dosage effects in a pillow parapraxis of 11p13 deletion, a topic of trisomy of all of 11p except 11p13, and a case of trisomy 11p13. The results were consistent with assignment of the catalase locus to 11p13 and its linkage with the WAGR complex (194070). Ass...If you hell qua non to get a full essay, order it on our website:
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