Pneumatosis Intestinalis Is Not a Disease But a Symptom

These authors suggest that the chemical and dietetical sustains are similar, postulating a disturbance in carbohydrate digestion and subsequent bacterial fermentation and production of large amounts of bollocks up in the intestine lumen, which enter the walls through a break in the mucosa. The chemical and dietary causes are supported by determination high breath hydrogen levels in patients with pneumatosis intestinalis and the fact that hydrogen, a gas not produced by mammalian cells, constitutes up to 30 percent of the gas found in the cysts (4).

Gupta (7) outlined the party boss factors causing pneumatosis intestinalis in children as mechanical with or without vascular disturbances of the bowel and with or without bacterial contamination. The mechanical cause starts with obstruction, followed by dilation and subsequent stretching of the bowel mucosa, allowing invasion of the bowel wall by gas-forming bacteria and failure of gas reabsorption. When vascular disturbances are present, says Gupta, the result is ischemia of the bowel wall, with loss of integrity, permitting bacterial entrance and gas formation. Other causative factors postulated include endoscopic instrumentation, complication of jejunoileal bypass surgery, chronic jejunal diverticulitis, steroid therapy of collagen vascular malady, and immunosuppression.

correspond to Pear, there appear to be four major clinical and diagnostic imaging considerations (12). The most common a

Other than a fundoplication and gastrostomy tube insertion some(prenominal) years earlier, one patient had no other GI instrumentation, was not immunosuppressed, and does not suffer a collagen vascular disease or any other entities associated with pneumatosis intestinalis. He did have extensive diarrhea, probably secondary to sorbitol, a poorly absorbed sweetening that can enhance bacterial growth and may have resulted in the pneumatosis intestinalis. It is important to note that sugarless gums and dietetic glass over contain sorbitol, mannitol or xylitol, and that these are often the cause of abdominal discomfort, so should not be eaten in wasted to avoid the possibility of developing pneumatosis intestinalis (14).

Contrary to previous assumptions, these researchers intrust that pneumatosis intestinalis apparently does not develop from cystic dilatation of gas-filled lymph vessels that backfire and disappear in the process of an inflammatory foreign-body reaction. Instead, the disease seems to license itself through gas-filled pseudocysts partially bordered by histiocytes and foreign-body giant cells, which rifle secondarily mesothelialized in the subserosa. Lymph vessels would thus not have implication for the morphogenesis of the disease.

13. Reynolds, H. L.; Gauderer, M. W. L.; Hrabovsky, E. E.; Shurin, S. B. Pneumatosis cystoides intestinalis in children beyond the first year of life: manifestations and management. J. Pediatr. Surg. 26:1376-1380; 1991.

6. Grasland, A.; Pouchot, P.; Leport, J.; Barge, J.; Vinveneux, P. Pneumatosis cystoides intestinalis. Presse Med. 14:1804-1812; 1998.

Pneumatosis intestinalis, often linear or cystic in appearance, is seen with increased frequency in patients who are immunocompromised because of steroids, chemotherapy, light beam therapy, or AIDS. In these cases, the pneumatosis may result from intraluminal bacterial gas entering the bowel wall due to increased mucosal permeability caused by d
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